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RHEUMATOLOGY CLINICAL SERVICE AT THE HOSPITAL SAN CARLOS
Name : 
RHEUMATOLOGY CLINICAL SERVICE AT THE HOSPITAL SAN CARLOS
Country: 
Spain
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The rheumatology department of this centre is a public research group that combines extensive experience on basic and clinical research on musculoskeletal diseases. We have conducted several research activities, including: • Basic research: Our research group if focused on two different subjects: o Study of the genetic basis of different musculoskeletal diseases, including rheumatoid arthritis (RA) and osteoarthritis. We collaborate with several national and international groups in the analysis of the genetic risk factors for RA and RA severity, including cardiovascular disease and radiological damage. o Study of the regenerative and immunomodulatory role of mesenchymal stem cells (MSCs) in musculoskeletal diseases. Our group is analyzing different aspects of MSCs osteogenic and chondrogenic differentiation, in heath and disease (osteoarthritis), and based on the location of the MSCs in the joint (i.e. bone marrow, subchondral bone and cartilage). We are analyzing the signaling path